Sleepless nights increase the risk of dementia

Poor sleep for a long time negatively affects the state of General human health, in particular, affects the cardiovascular and immune systems. Scientists from the University of California, Irvine (USA), whose work is reported by Quartz, claim that poor sleep quality also plays a significant role in the development of dementia in late adulthood. 

Disturbance of the regime and insufficient number of hours of sleep in young and middle age increase the risk of developing Alzheimer's disease in adulthood — this is the conclusion of American scientists, presenting a report at a conference on brain health, held this week (October 29) in Washington at the School of public health at the Milken Institute. 

In 2017, their group published a paper proving a link between poor sleep quality and accelerated accumulation of toxic amyloid and Tau proteins in people with a genetic predisposition to Alzheimer's disease. 

Subsequent work confirmed this theory. An experiment conducted by experts from the National Institutes of Health in Bethesda (USA), found that healthy participants who had to wake up in the middle of the night on the alarm clock, the next day were observed with an increased level of amyloids. Other studies have also shown that older people who suffer from insomnia have a higher concentration of Tau proteins.

But this connection can be reversed: excessive accumulation of amyloid and Tau proteins can lead to sleep disorders. Thus, an autocatalytic process can be observed: the worse person sleeps, the more toxic proteins accumulate, causing him to sleep even worse. Improving sleep quality can help cleanse the body of these deposits and reduce the risk of Alzheimer's disease.

Experts recommend spending an average of about seven hours a day for sleep. The regime of the day should be built so that the person gets enough hours to sleep in

The authors of the report note that if sleep plays a significant role in the development of dementia, it is necessary to make it a target for the prevention and treatment of age-related diseases.

Oct. 31, 2019, 10:41 a.m.

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