Biomarker helps detect Alzheimer's and Huntington's 20 years before symptoms

Two independent studies, one by specialists from University College London and the other by the Massachusetts General Hospital team, confirm the role of NfL protein in the development of neurodegenerative diseases such as Alzheimer's and Huntington's. Scientists argue that the level of this protein can predict their development decades before the first symptoms begin to appear. It is believed that if such symptoms have already occurred, most of the neurological damage can be irreversible, so learning to detect disease quickly and at an early stage of development is an important task for scientists and doctors. New Atlas tells us about the biomarker.

NfL protein is released as a result of brain cell damage. It is a biomarker that helps to detect diseases such as Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis at an early stage. 

Two new studies confirm that this protein may also indicate Huntington's disease 24 years before the first symptoms appear, and Alzheimer's disease 22 years before. The scientists found this out by analyzing blood and cerebrospinal fluid samples from people with a corresponding genetic mutation.

Thus, valuable evidence has emerged that NfL levels can be an effective tool for diagnosing neurodegenerative disorders at their earliest stages of development, many years before symptoms emerge.

June 2, 2020, 4:10 p.m.

Similar articles:

Dryness and pain in the eyes might be a sign of increased glucose levels in diabetes

Dry eyes, namely the lack of secretion from the meibomian ...

The cervicovaginal microenvironment is an early biomarker of cervical cancer

Cervical cancer is one of the most common forms of ...

Three tipping points of aging are 34, 60 and 78 years

Researchers at Stanford University School of Medicine have identified proteins ...

Two signs which simultaneously increase the risk of dementia

Decreased walking speed and memory impairment are two of these ...

The mediator between the two biomarkers of Alzheimer's disease is found

A group of researchers from the University of Alabama at ...

The rate of aging depends on iron concentration in the blood

Biological aging is characterized by the gradual degradation of the ...

A way to influence the gene that triggers eye aging discovered

Scientists from the University of California, San Diego (USA) have ...

Human aging occurs in four biochemical types

Aging is a process common to all living beings. However ...

COOKIE

Our site collects information using cookies to be more convenient and customized to your needs interests. The purposes of the use of cookies are defined in Policy the processing of personal data .If you agree to continue to receive cookies, please click the "Accept" button. If you don't agree or want to resolve this issue later, please change your browser cookie settings.