Complex diagnosis of Alzheimer's will detect the disease in advance with an accuracy of 90%

Scientists at Cardiff University (UK) have developed a prediction method of the development of Alzheimer's disease with an accuracy of 90%. The diagnostic model, called multiplex (polygenic), is based on all available information on risk factors for the development of this type of age-related dementia. 

Today many signs have been revealed which allow to judge about the likelihood of Alzheimer's disease development, among which are biochemical and behavioral markers and brain scan data. Over 50 genes have also been found to play a key role in the appearance of Alzheimer's disease. However, according to experts, the available data is often used in a fragmented manner. The essence of creating a multiplex diagnostic model is in generalizing all available knowledge about the risk of disease development. 

Polygenic model allows to make a conclusion on the basis of summary information about genetic risks, disorders of cellular processes (for example, changes in brain immune system, accumulation of toxic proteins, cholesterol processing disorders, etc.). The multiplex model also takes into account the presence of other diseases that increase the risk of Alzheimer's development, as well as environmental and social factors. 

Disorders leading to Alzheimer's disease begin 20 years before the first symptoms appear, and sometimes even earlier. Specialists argue that a comprehensive approach can detect up to 79% of late onset Alzheimer's and over 90% of early onset Alzheimer's cases. 

March 10, 2020, 11:33 a.m.

Similar articles:

New biosensor accurately diagnoses Alzheimer's disease from a drop of blood

A research team from the Korea Institute of advanced technology ...

You can influence fat metabolism in the body by using odors

Scientists at Howard Hughes Medical Institute's Center for Aging at ...

Protein misfolding as a risk marker for Alzheimer’s disease – up to 14 years before the diagnosis

In symptom-free individuals, the detection of misfolded amyloid-β protein in ...

The vaccine against tuberculosis reduces the risk of developing Alzheimer's fourfold

BCG vaccination is designed to prevent tuberculosis. However, its ability ...

The postwar generation's brain started to degrade

Scientists at Ohio University concluded that people born between 1948 ...

Special lighting will help to cope with insomnia in Alzheimer's

Violation of daily biorhythms is one of the risk factors ...

Life expectancy in dementia will be predicted by the table

Scientists from the Karolinska University (Netherlands) have developed a method ...

Scientists have identified a new cause of Alzheimer's disease

A team of researchers from Case Western Reserve University (USA ...

COOKIE

Our site collects information using cookies to be more convenient and customized to your needs interests. The purposes of the use of cookies are defined in Policy the processing of personal data .If you agree to continue to receive cookies, please click the "Accept" button. If you don't agree or want to resolve this issue later, please change your browser cookie settings.