Green tea component may prevent tumor formation

A new paper published in Nature Communications shows that a compound found in green tea promotes the accumulation of a protein that inhibits the formation of cancer cells.

P53, a protein that, according to Chunyu Wang, the study's lead author and a professor of biological sciences at Rensselaer Polytechnic Institute, may be the most important target for fighting cancer. Its function is to repair DNA and trigger apoptosis (programmed cell death) in old or damaged cells.

Epigallocatechin gallate (EGCG), the main antioxidant found in green tea leaves, helps the body neutralize the oxidative effects of free radicals. However, that has not been proven to be its only beneficial function. Scientists found that EGCG can interact directly with the protein p53, thus blocking its natural degradation in the body.

Thus, increasing the level of p53 can be used as a therapy for cancer.

Feb. 15, 2021, 12:17 p.m.

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