Diseases could be predicted by microbiome with an accuracy of 50% and possible death within 15 years

Science has published an analysis of two recent studies on the relationship between intestinal microbiome and diseases, including those leading to death. For instance, scientists at Harvard University conducted a meta-analysis of 47 studies, which revealed that changes in the microbiome can predict the development of 13 common diseases. Among them - hypertensive disease, asthma, schizophrenia, etc. For some diseases, such as colorectal cancer, the accuracy of the prognosis was 50%.

Specialists from Harvard compared the accuracy of "predictions" based on the analysis of microbial landscape with genetic expertise. For 12 of the 13 diseases, the microbiomic diagnosis was more accurate than the genomic one. The only exception was diabetes mellitus, where genomic analysis was more effective.

According to scientists, the high diagnostic value of microbiome analysis in comparison with genetic analysis is due to the fact that the composition of the microbiota is determined not only by hereditary factors, but also reflects the lifestyle of man, the nature of his diet. That is the sum of interaction of genetic and behavioral factors. 

The second study mentioned by Science was conducted by scientists from Turku University (Finland). During 15 years scientists observed a group of 7211 people, periodically making up the profile of intestinal microbiome of participants and analyzing the relationship between the composition of microbiota, the risk of disease and death. People whose intestines had an increased content of opportunistic bacteria, including some E. coli and salmonella, were found to have a 15% higher risk of dying within the next 15 years than those who had no such changes.

One of the reasons why the presence of a high concentration of such microbes in the microbiome leads to increased risk of death, according to scientists, is chronic inflammation in the intestine: it increases the permeability of the intestinal wall to dangerous microbes, toxic substances and allergens. 

Jan. 24, 2020, 11:39 a.m.

Similar articles:

AI has been taught to predict the development of diseases

Japanese experts from the universities of Hirosaki and Kyoto have ...

People with Parkinson's disease are more likely to suffer from vision problems

Scientists at the University Medical Centre in Redbud, the Netherlands ...

Walking pace and hearing acuity will predict life expectancy after a heart attack

Experts from Yale University believe that the data on the ...

Loneliness shortens a person's life expectancy

A study by Danish scientists involving more than 13,000 ...

Research: People born in December have the healthiest heart

Scientists from Harvard medical school (USA) and Vienna Medical University ...

The brain can only perceive someone else's death, not its own

Everyone knows that he will die, but this knowledge is ...

Want to live longer? Stay in university

Scientists from Yale University and the University of Alabama surveyed ...

Poor people die more often – a study involving 70 million people proved

People with low incomes die more frequently than wealthy people ...

Working conditions are closely linked to mental health and the risk of death

A new study from the Kelly School of Business at ...

COOKIE

Our site collects information using cookies to be more convenient and customized to your needs interests. The purposes of the use of cookies are defined in Policy the processing of personal data .If you agree to continue to receive cookies, please click the "Accept" button. If you don't agree or want to resolve this issue later, please change your browser cookie settings.