Found a protein that can protect against brain aging

An international team of scientists from Canada, the United States and Germany found that the CD33 protein in microglia cells can reduce the risk of developing Alzheimer's disease. The results of the study are published in the journal Communications Biology.

Microglia is a macrophage cell of the immune system that cleans the brain of amyloid plaque clusters which cause Alzheimer's disease and damage the nervous system. The purification process is carried out by phagocytosis - by absorbing and digesting damaged and harmful molecules.

Experts have found out that the presence of working CD33 protein in microglia cells can protect the brain from dementia. However, less than 10% have a useful version of this protein. Scientists believe that if they manage to make a more common variant perform a similar function as a result of genetic manipulation, there will be an effective remedy for Alzheimer's disease: with a useful version of the protein, the brain will be independently cleared of amyloid accumulations.

Dec. 6, 2019, 10:37 a.m.

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