Human neurons "implanted" in the brain of mice will help with Alzheimer's

There are many diseases such as stroke, Alzheimer's disease - in which severe manifestations are caused by the death of nerve cells. Scientists from the University of Brussels conducted a unique experiment: they transplanted stem cells that are precursors of human neurons into the brain of mice and watched the situation unfold.

It turned out that the nerve cells perfectly "fit" into the new environment. But at the same time, they developed according to their own scenario, focusing on their own biological clock. After a while, they built into the neural networks of the mouse brain, began to participate in the processing of information, to respond to environmental stimuli.

"Human cells even showed different responses depending on the type of stimulus, indicating a surprisingly high degree of accuracy in the connections between the transplanted cells and the host mouse neural networks," noted the scientists who conducted the study. 

According to experts, this unusual experiment clearly demonstrated how the formation of complex neural networks under the influence of genetic information, environmental signals and behavior. Continuing research in this direction, scientists will be able to understand how the defects in neural circuits leading to the development of diseases emerge.

Also, the work of Belgian specialists opens up new prospects for the correction of disorders arising from stroke, Alzheimer's disease and other brain lesions: the experiment showed that dead or defective nerve cells can be replaced by young neurons. 

Nov. 25, 2019, 12:09 p.m.

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