New biosensor accurately diagnoses Alzheimer's disease from a drop of blood

A research team from the Korea Institute of advanced technology has developed a high-precision biosensor for detecting Alzheimer's disease. Diagnosis is performed using a drop of the patient's blood, where the main biomarkers of neurodegenerative disease are measured. The development is reported by the press service of the Institute.

If you diagnose Alzheimer's at an early stage, you can significantly slow down its development. However, modern methods often have low accuracy and are expensive. 

Korean scientists have found a solution to this problem: they have developed a device that detects and accurately measures the main biomarkers of the disease in human blood plasma and, importantly, has a low cost of manufacture. This is a highly sensitive biosensor based on high-density aligned carbon nanotubes. Such nanotubes improve the sensitivity of the device by 100 times compared to others created based on carbon tubes.

The biosensor detects concentrations of beta-amyloid 42, beta-amyloid 40, total and phosphorylated Tau protein-typical markers of the disease. Tests conducted on patients with Alzheimer's disease showed that its sensitivity was 90%, and the average accuracy rate was about 87%. Next, the scientists intend to conduct testing on volunteers who are only suspected of developing the disease. 

Feb. 13, 2020, 10:34 a.m.

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