A step towards creating a "universal pill" for diseases: scientists have found a way to limit inflammation

Many diseases are caused by inflammatory processes in the body. A research team from Trinity College in Dublin has found a major "switch" that can suppress excessive immune cell activity to limit inflammation. It is reported by the press service of the College.

The team identified a new target for treating diseases caused by overactive immune cells, such as multiple sclerosis or psoriasis - the PKM2 protein. 

PKM2 is involved in the processing of glucose by cells for energy production. However, as it turned out, this protein also affects the immune system, regulating the activity of two types of cells-Th17 and Th1, involved in the development of autoimmune diseases.

Scientists have found that manipulations with PKM2 block excessive activity of Th17 and Th1 and thus suppress the inflammatory process.

So far, the authors have not reported on the mechanism of this therapy, however, according to the authors, this is an important discovery that could lead to the creation of a "universal cure" for many diseases caused by inflammation.

Nov. 25, 2019, 10:59 a.m.

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