Citrus fruits can protect the heart and blood vessels

Scientists have studied naringin, a natural flavonoid that gives bitterness to grapefruits and tangerines. It turned out that it is able to reduce inflammation, protect the heart from overload and help the vessels to remain elastic. In experiments on animals and cells, naringin reduced damage during heart attacks and blocked dangerous inflammatory reactions. Even in humans, the first results are encouraging: regular consumption of grapefruit juice improved the flexibility of the arteries. But in order for the drug to become part of medicine, large-scale clinical trials are needed.

Citrus fruits can protect the heart and blood vessels

Who would have thought that a slight bitterness in grapefruit could hide the medicine of the future? Naringin, a natural compound from citrus fruits, is increasingly attracting the attention of the medical community.

Research shows: this substance can not only fight inflammation, but also protect heart cells from death. In laboratory experiments, naringin reduced damage during ischemia and helped mitochondria, the energy stations of cells, to work more stably.

In animal experiments, the results were even better. In rats and rabbits, the substance reduced the formation of atherosclerotic plaques, normalized blood pressure and prevented overload of the heart muscle. It is noted that naringin acts in several ways at once — it reduces oxidative stress, calms inflammatory processes and supports the production of protective molecules.

There is not much research data on humans so far, but the first steps are encouraging. In one study, postmenopausal women who drank grapefruit juice for six months showed more flexible vessels. In another case, taking naringin improved metabolic rates and reduced arterial stiffness.

However, there are obstacles. Naringin is poorly absorbed: less than 5% of the substance enters the body. Work is currently underway on new delivery methods, for example, using liposomes. In addition, scientists have yet to determine the optimal dose and ensure safety with long-term use.

Published

August, 2025

Category

Medicine

Duration of reading

1—2 minutes

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