Daily multivitamin intake can slow down biological aging
A two-year clinical trial has shown that daily multivitamin intake slows down the rate of cellular aging in older adults, with the most pronounced effect observed in those whose bodies age faster than the calendar schedule. Researchers at the Mass General Brigham Health System analyzed data from the large-scale randomized COSMOS study to investigate how vitamin complexes affect biological age. Unlike conventional age, biological age reflects the state of the body at the cellular level. To assess it, scientists used five different epigenetic clocks, which are special markers that track changes in DNA (methylation) associated with the risk of mortality and overall body aging.
The study involved 958 healthy volunteers, with an average chronological age of 70 years. The participants were divided into two groups, one taking a standard multivitamin daily, while the other received a placebo. After two years of regular intake, blood tests showed a slowdown in biological aging in all five types of epigenetic clocks. On average, the effect was equivalent to a four-month rejuvenation over two years compared to the control group.
What was particularly interesting was that the multivitamins were most beneficial for those participants whose biological age was already ahead of their actual age at the beginning of the study. For these individuals, taking the supplements proved to be an effective way to slow down their accelerated aging process. The researchers emphasize that this opens up the possibility of using affordable and safe methods not only to prolong life, but also to improve its quality in older age.
Despite the promising results, the researchers plan to continue their work to determine whether the anti-aging effects persist after discontinuing the vitamin intake. The COSMOS team also intends to find out how these changes at the cellular level are related to real clinical results, such as a reduced risk of cancer, cataracts, and improved cognitive abilities. At the moment, the work confirms that multivitamins can be an important element in the prevention of age-related changes.
Published
March, 2026
Category
Medicine
Duration of reading
2-3 minutes
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Source
Scientific Journal Nature Medicine. Article: Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial
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