A new supplement can safely replenish iron
Iron deficiency remains one of the most common causes of fatigue, headaches, and anemia worldwide. Traditional iron preparations do increase its level, but they often cause side effects such as inflammation, abdominal pain, and intestinal microflora disorders. The triple combination of iron, probiotics, and prebiotics helps to replenish levels safely. A study published by the American Chemical Society paves the way for the safe treatment of anemia.
Anemia occurs when the body lacks red blood cells, oxygen—carrying cells. In iron deficiency anemia, the main cause is a lack of iron in the diet or its poor absorption.
Conventional drugs contain large amounts of indigestible iron, which remains in the intestine and can cause irritation. To mitigate the effect, probiotics are often added to them — friendly bacteria that protect the mucous membrane and restore the microflora.
Researchers led by Punem Sagar and Nitin Kumar Singhal have invented an improved version — a triple supplement consisting of:
- the iron-containing complex,
- Lactobacillus rhamnosus bacteria,
- and dietary fiber from millet, which acts as a prebiotic — food for beneficial microorganisms.
This combination proved to be more effective than the usual forms of iron, and at the same time safe for the gastrointestinal tract.
In experiments on mice with iron deficiency anemia, the new supplement completely restored hemoglobin levels in just two weeks. The tests showed:
- iron was absorbed as efficiently as in healthy animals.,
- There was no inflammation in the intestine,
- and the composition of the microbiota has returned to normal.
In addition, activation of genes related to iron transport was noted — that is, the body began to process and distribute the trace element naturally again.
“Our discovery offers a biomaterial approach to iron delivery that not only replenishes stores, but also preserves intestinal health,” says study author Punem Sagar.
Published
October, 2025
Category
Medicine
Duration of reading
2–3 minutes
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Source
Scientific Journal ACS Applied Materials & Interfaces. Article: «Hyaluronic Acid Hydrogel-Based Oral Delivery of Iron Supplemented with Probiotic and Prebiotic Ameliorates Iron-Deficiency Anaemia»
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