Memory returns even with severe brain damage
For a century, the medical community has been convinced that the death of neurons in dementia is an irreversible process. All the efforts of the doctors were aimed only at slowing down the decline of personality a little, rather than returning the person to his former consciousness. But a recent breakthrough by a team from Cleveland has literally turned the understanding of biology upside down, proving that even a severely damaged organ is able to reanimate its functions and literally heal itself from the inside out.
The main key to salvation turned out to be a special molecule NAD+, which acts as the main fuel for every cell in our body. With age, its reserves naturally deplete, and with the development of pathologies, this deficiency becomes critical, depriving the tissue of the forces necessary for basic survival. This study has clearly shown that if you artificially maintain the right energy balance, you can not only stop the disease, but also turn back time.
To confirm this bold theory, scientists used experimental animals with the most complex forms of genetic mutations that mimic the human condition. Toxic proteins accumulated in the body of the test subjects, blood vessels collapsed and connections between cells disappeared, which led to a complete loss of memory. To the surprise of the group, after the course of therapy, the tissues not only cleared of dangerous deposits, but also restored the ability to learn to the level of healthy individuals.
The fundamental difference of the new technique is the use of a unique substance P7C3-A20 instead of the usual additives from the store. The fact is that uncontrolled intake of popular vitamins can raise energy levels to dangerous limits, which in some cases provokes the growth of tumors. The created tool acts selectively and gently, helping the system to cope with stress itself and maintain balance without unnecessary risk to health.
Such painstaking work opens the door to a new era, where a terrible diagnosis ceases to sound like the final point in a patient’s life. The author of the project, Andrew Pieper, emphasizes that their discovery gives a powerful impetus to hope.: Our mind has hidden reserves for self-repair that we didn’t even know about before. This changes the very paradigm of treatment, turning medicine from a maintenance system into a tool for a full return to a full life.
Recent observations of the state of biological markers in the blood confirm that recovery occurs at a deep molecular level. The results obtained in the near future will become the foundation for large-scale human trials in order to transfer success from laboratories to real medical practice. Experts aim to find additional ways to enhance this effect in order to finally overcome age-related mental changes.
Published
December, 2025
Category
Science
Duration of reading
2-3 minutes
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Source
Scientific Journal Cell Reports Medicine. Article: «Pharmacologic reversal of Alzheimer’s disease in mice reveals potential therapeutic nodes in human brain»
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