Vitamin K deficiency impairs memory and increases inflammation in the brain

A new study by scientists published in The Journal of Nutrition has shown that vitamin K deficiency can not only impair memory, but also increase inflammation in the brain. The area responsible for learning and memorization is particularly affected. Here’s how it relates to your diet and why it’s important not to forget the greens on your plate.

Vitamin K deficiency impairs memory and increases inflammation in the brain

Researchers from the Center for Nutrition and Aging at Tufts University (USA) have drawn attention to the little-studied effect of vitamin K on brain function. Their goal is to understand why the ability to memorize and learn decreases with age, and what role the lack of this element plays in this.

Scientists paid special attention to the hippocampus – the area of the brain associated with memory. Using the example of middle-aged mice, the experts noticed that the scarce intake of vitamin K increases inflammatory processes and reduces the brain’s ability to renew itself – the hippocampus slows down the birth of new neurons. This directly affects cognitive function.

Vitamin K is found in broccoli, spinach, peas, Brussels sprouts and other greens. It was previously known that this vitamin is important for blood clotting and vascular health. But now there is mounting evidence of its role in maintaining mental clarity.

One group was given a nutritious diet with adequate levels of vitamin K, while the other group was given a reduced diet. After six months, the rodents were asked to take two tests: object recognition and spatial orientation. Those who were deficient in the vitamin performed noticeably worse.

The hippocampus of mice with vitamin K deficiency showed fewer new cells and more signs of inflammation. Especially the number of activated microglia – cells that normally protect the brain, but in excess trigger destructive processes.

The birth of new neurons is essential for memory, learning and adaptation. When this process slows down, a person can experience difficulty remembering, decreased attention span and even an increased risk of neurodegenerative diseases.

There is no need to rush out for jars of vitamins. It is much more effective to adjust the diet. A nutritious diet rich in green vegetables is not just a recommendation, but a really workable way to support your brain and body.

Tufts University is studying the mechanisms in animal models, and in parallel, experts from Rush Medical Center in Chicago are observing elderly people, analyzing how nutrition affects memory and longevity. This approach makes it possible to find real leverage.

Good nutritional habits are established not in old age, but long before it. Regular consumption of vitamin K products can be a simple but effective step towards keeping a clear mind and vigor at any age.

Published

April, 2025

Duration of reading

3-4 minutes

Category

Medicine

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