Saffron helps with depression and Alzheimer’s

As we age, anxiety and depression become more common. In addition, the elderly have an increased risk of developing mild cognitive impairment, which can develop into dementia. There are few drugs that can really help. But there are more than enough side effects.

Experts suggest adding saffron to the diet. Its active ingredients — crocin, crocetin and safranal — work in several directions at once. They increase the level of hormones of joy, fight inflammation, act as antioxidants and even protect the brain from destruction.

We analyzed data from dozens of clinical trials and came to the conclusion that saffron works no worse for mild to moderate depression than popular antidepressants like fluoxetine. At the same time, he has fewer side effects — a maximum of mild nausea or a change in appetite.

In the group of people with memory impairments, saffron improved cognitive abilities no worse than standard drugs like memantine. I was particularly impressed that the effect was achieved at the same dose in all studies — 30 mg per day.

What is behind this action? Saffron’s working mechanisms are impressive. It helps neurotransmitters like serotonin and dopamine, improves communication between nerve cells, reduces inflammation in the brain, increases resistance to stress, and even promotes the growth of new neurons.

Despite promising results, saffron has not yet become an official medicine. It is difficult to standardize it — the content of useful substances depends on the variety, harvest season and processing method. In addition, the spice remains expensive, and its long-term safety has yet to be confirmed.

Nevertheless, the researchers are not losing their enthusiasm. They believe that saffron can be a useful addition to traditional therapy, especially for those who find it difficult to tolerate conventional drugs. The main thing is to continue to research and follow reasonable dosages.