Scientists named the main cause of obesity

A group of scientists from the Brazilian University of Campinas has published the results of a study that allowed to establish the root cause of obesity. This is reported in a press release on the EurekAlert portal.

What you will learn in the article

  • How Brazilian researchers studied whether hypothalamic neuron changes or microbiota changes appear first in obesity
  • Why mice were given a diet high in saturated fats to induce metabolic disorders
  • How neurosecretory cells of the hypothalamus changed before intestinal microflora composition changed
  • Why death of satiety-regulating neurons is described as starting a chain reaction in the body
  • Why researchers next need to find ways to restore neurons lost because of an unbalanced diet

Table of Contents

Scientists named the main cause of obesity

According to Dr. Licio Velloso, who presented a report at the conference of the Foundation for Scientific Research of the State of Sao Paulo, not so long ago, scientists were able to establish that rapid weight gain is caused by changes in the intestinal microflora and the death of specific neurons in the hypothalamus. However, until now, it has been a mystery which of these processes starts first.

To find out, scientists conducted a series of experiments on mice. The rodents were prescribed a special diet high in saturated fats, which was supposed to lead to metabolic disorders.

On the very first day of the experiment, the researchers recorded changes in the neurosecretory cells of the hypothalamus, while the composition of the intestinal microflora remained the same for two weeks. As a result, scientists came to the conclusion that it is the death of neurons that regulate the feeling of satiety that leads to a “chain reaction” throughout the body.

Now, experts will have to find a way to restore the neurons lost due to an unbalanced diet. “This is only the first step, but perhaps it will help achieve a therapeutic solution to the problem of obesity in the future,” said Velloso.

Source: RIA Novosti

Don’t miss the most important science and health updates!

Subscribe to our newsletter and get the most important news straight to your inbox

Key takeaways

  • The study was conducted by scientists from the Brazilian University of Campinas
  • Rapid weight gain had been linked with intestinal microflora changes and death of specific hypothalamic neurons
  • Mice received a special diet high in saturated fats during the experiment
  • Hypothalamic neurosecretory cells changed on the first day of the experiment
  • Intestinal microflora composition remained unchanged for two weeks

Published

June, 2024

Duration of reading

1-2 min

Category

The brain and nervous system

Share

Table of Contents

Send us a message